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Newborn & Infant Vaccinations UK — The Complete Schedule Explained

The UK routine immunisation schedule from 8 weeks — what vaccines are given, when, and what to expect afterwards.

📅 Last reviewed: March 2026
5 min read
🔬 Source: NHS · PHE · JCVI
Kofi — Baby Safety Lab
Kofi
Pharmacy-Trained Health Educator
MSc Pharmaceutical Science — RGU
BPharm — Bachelor of Pharmacy
NHS & WHO guideline-trained

The question I see most often from new parents is not about the vaccines themselves — it is about the timing. Why so early? Why so many at once? The answers are rooted in immunology, not convenience.

Why the Schedule Is What It Is

Maternal immunity — antibodies passed from mother to baby during pregnancy — begins to wane from around 2 months. The 8-week vaccines are timed to provide protection precisely as that window closes. Starting later leaves your baby unprotected when these diseases are most dangerous.

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Pharmacy Fact
A baby's immune system is not overwhelmed by multiple vaccines at one appointment. Babies encounter thousands of antigens every day in their normal environment. The vaccines at 8 weeks represent a tiny fraction of what the immune system processes daily.

The 8-Week Vaccines

8 weeks: 6-in-1 (diphtheria, tetanus, whooping cough, polio, Hib, hepatitis B) · Rotavirus (oral) · MenB

12 weeks: 6-in-1 (second dose) · Rotavirus (second dose) · PCV

16 weeks: 6-in-1 (third dose) · MenB (second dose)

12 months: Hib/MenC · MMR · PCV booster · MenB booster

What to Expect After

After the MenB vaccine, give infant paracetamol — one dose at vaccination, two further doses 4–6 hours apart. Dose by weight. Sore leg, fussiness, and low-grade fever are normal for 24–48 hours.

Common Questions

“My baby has a cold — should we postpone?” A mild illness is not a reason to postpone. Reschedule only if your baby has a high fever — and reschedule as soon as possible.

“Can vaccines cause the disease?” No. The NHS schedule vaccines do not contain live viruses capable of causing infection, with the exception of rotavirus which contains a weakened live virus that cannot cause disease in a healthy baby.

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Vaccination Schedule — Key Dates
  • 8 weeks: 6-in-1 · Rotavirus · MenB
  • 12 weeks: 6-in-1 · Rotavirus · PCV
  • 16 weeks: 6-in-1 · MenB
  • 12 months: Hib/MenC · MMR · PCV · MenB boosters
  • After MenB: give paracetamol by weight
  • Mild cold = still attend. High fever = reschedule promptly

Sources

NHS Childhood immunisation · PHE Immunisation Green Book · WHO · Reviewed April 2026.

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For Educational Purposes Only
Baby Safety Lab Ltd (Company No. 884811, registered in Scotland). Always consult your GP, health visitor, or NHS 111. In an emergency call 999.